FAQ

OVACARE ® is a food supplement for women of reproductive age. It contains a natural mix of vitamins, metals, and antioxidants, such as Folic acid, Vitamin E (tocopherol), Grape seed extract, Melatonin, Myoinositol, Coenzyme Q10, L-Arginine, and α-lipoic acid.

The supplement’s ingredients act by enhancing the body’s antioxidative mechanisms and, thus, reducing oxidative stress, ensuring the necessary metabolic substrate for the ovarian tissue, and improving the effect of growth agents which promote folliculogenesis.

Folic acid is recommended for all women who are trying to conceive, with the aim to reduce the risk of harm to the embryo’s neural tube; miscarriage; embryo under-development, as well as the risk of foetal congenital heart disease, or even speech – language disability. Women who wish to gestate should have enough folic acid a month before getting pregnant.

Vitamin Ε and grapeseed extract are components with a strong antioxidant effect, offering protection to the egg (oocyte) from lesions caused to their DNA by free radicals; they also provide a shield to the egg’s cell membrane, which helps prevent early apoptosis while improving the egg’s mitochondrial function.

Melatonin may be helpful for women, mainly 35 to 40 years of age, who have low-quality eggs. Melatonin aids oocyte maturation; granulosa cell luteinisation by improving progesterone production and contributes to embryo growth through lowering the risks related to embryo neural tube abnormalities and gestation complications.

It also reinforces inositol and folic acid effectiveness, having a crucial independent or synergistic action, as melatonin can easily go through both cell membrane and blood-brain barrier.

Melatonin contributes to clinical pregnancy; also, its role as a biomarker for ovarian reserve is investigated.

Myoinositol, according to research, is involved in various stages of human reproduction. It is a key intermediate molecule to second messengers, but also an essential component of cell membrane phospholipids involved in several biological processes. Its unique chemical structure allows myoinositol to “enter” and “exit” cells, playing a crucial role.

Increased myoinositol concentration in follicular fluid appears to benefit follicle maturation and is indicative of high-quality eggs (oocytes).

Myoinositol is highly effective in metabolic and hormonal disorders caused by Polycystic Ovary Syndrome related to subfecundity, also inducing hormonal balance at the productive phase of women’s menstrual cycles.

A-lipoic acid is a strong antioxidant, which is able to immediately eliminate reactive oxygen species (ROS) and has a potential to react with other antioxidants, such as glutathione, coenzyme Q10 and vitamins E and C, thus improving their antioxidative action and contributing to the regeneration of oocytes’ cellular structures.

A-lipoic acid helps carbohydrates metabolism and energy production, also creating an antioxidative complex, which is important for the proper function of cellular processes and restitution of the oocyte’s mitochondrial lesions; this is especially relevant for women who receive IVF and present fertilised eggs with abnormal morphology. It also has significant effect in overweight women with fertility problems who do not suffer from metabolic syndrome or Polycystic Ovary Syndrome.

Coenzyme Q10 is a strong antioxidant which occurs naturally in the body but is also available in foods or as a food supplement. It is found on the membrane of nearly every cell of the body and is necessary for the formulation of mitochondrial ATP, which is responsible for generating cell power. Regular embryo development until it reaches the blastocyst stage depends on the oocyte’s mitochondrial energy background, since mitochondria are uniquely contributing to the embryo formation. Most studies support coenzyme Q10 supplementary intake by women who will undergo in vitro fertilization, at a recommended dose of 600 mg daily, for about 2 months.

L-Arginine is an activated amino-acid and helps improve blood circulation in ovarian stroma through vasodilation and its indirect, synergistic antioxidant effects. L-Arginine is found in many foods and when taken for a certain amount of time, it enhances egg quality in women over the age of 35, while it doesn’t seem to increase the low number of ovarian follicles at the onset of their cycles.